Gert De Hertogh Selected Research

Epiretinal Membrane (Epiretinal Membranes)

1/2022	Proprotein convertase furin is a driver and potential therapeutic target in proliferative diabetic retinopathy.
5/2020	Interleukin-11 Overexpression and M2 Macrophage Density are Associated with Angiogenic Activity in Proliferative Diabetic Retinopathy.
2/2020	Galectin-1 studies in proliferative diabetic retinopathy.
1/2020	Evaluation of Proteoforms of the Transmembrane Chemokines CXCL16 and CX3CL1, Their Receptors, and Their Processing Metalloproteinases ADAM10 and ADAM17 in Proliferative Diabetic Retinopathy.
10/2019	Cross-Talk between Sirtuin 1 and the Proinflammatory Mediator High-Mobility Group Box-1 in the Regulation of Blood-Retinal Barrier Breakdown in Diabetic Retinopathy.
6/2018	Association of 150-kDa oxygen-regulated protein with vascular endothelial growth factor in proliferative diabetic retinopathy.
2/2018	Differential expression and localization of human tissue inhibitors of metalloproteinases in proliferative diabetic retinopathy.
1/2018	Unbalanced Vitreous Levels of Osteoprotegerin, RANKL, RANK, and TRAIL in Proliferative Diabetic Retinopathy.
1/2018	Matrix metalloproteinase-14 is a biomarker of angiogenic activity in proliferative diabetic retinopathy.
1/2017	Association of HMGB1 with oxidative stress markers and regulators in PDR.

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Gert De Hertogh Research Topics

Disease

31	Inflammation (Inflammations) 01/2022 - 09/2008
24	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2022 - 01/2013
22	Neoplasms (Cancer) 12/2021 - 09/2008
20	Ulcerative Colitis 11/2022 - 02/2007
18	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 06/2022 - 11/2009
18	Epiretinal Membrane (Epiretinal Membranes) 01/2022 - 01/2013
15	Crohn Disease (Crohn's Disease) 10/2021 - 04/2005
10	Colitis 01/2021 - 09/2003
7	Colorectal Neoplasms (Colorectal Cancer) 01/2020 - 09/2008
5	Hypoxia (Hypoxemia) 01/2022 - 02/2015
5	Fibrosis (Cirrhosis) 01/2020 - 09/2008
5	Pouchitis 11/2019 - 01/2008
4	Adenocarcinoma 12/2021 - 07/2010
3	Diarrhea 06/2022 - 01/2016
3	Necrosis 11/2019 - 01/2018
3	Neoplasm Metastasis (Metastasis) 01/2016 - 07/2010
3	Carcinoma (Carcinomatosis) 12/2014 - 07/2010
2	Dyspepsia (Indigestion) 01/2021 - 10/2020
2	Intestinal Failure 01/2021 - 01/2019
2	Failure to Thrive 05/2020 - 12/2016
2	Dysbiosis 01/2020 - 01/2018
2	Reperfusion Injury 01/2020 - 01/2017
2	Ischemia 01/2020 - 01/2017
2	Portal Hypertension 12/2018 - 11/2012
2	Esophageal Neoplasms (Esophageal Cancer) 05/2018 - 07/2010
2	Fatigue 12/2017 - 01/2016
2	Celiac Disease (Celiac Sprue) 09/2015 - 08/2015
2	Granuloma 04/2012 - 02/2012
1	Collagenous Colitis 06/2022
1	Dyspnea (Shortness of Breath) 04/2022
1	Dehydration (Water Stress) 04/2022
1	Anosmia 04/2022
1	COVID-19 04/2022
1	Parkinsonian Disorders (Parkinsonism) 10/2021

Drug/Important Bio-Agent (IBA)

16	EnzymesIBA 01/2021 - 07/2010
14	ImmunosorbentsIBA 01/2020 - 07/2010
12	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2021 - 07/2010
10	Infliximab (Remicade)FDA Link 11/2019 - 02/2007
9	Biomarkers (Surrogate Marker)IBA 10/2021 - 06/2010
9	Proteins (Proteins, Gene)FDA Link 01/2021 - 07/2010
7	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2021 - 09/2008
6	Retinaldehyde (Retinal)IBA 01/2022 - 02/2015
6	CytokinesIBA 01/2021 - 04/2012
6	Dextrans (Dextran)FDA Link 01/2020 - 11/2016
5	vedolizumabIBA 01/2022 - 09/2017
5	Matrix Metalloproteinases (MMPs)IBA 02/2018 - 01/2013
4	Anti-Bacterial Agents (Antibiotics)IBA 01/2020 - 04/2005
4	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2020 - 01/2017
4	Messenger RNA (mRNA)IBA 01/2018 - 10/2009
3	Ustekinumab (CNTO 1275)FDA Link 11/2022 - 10/2019
3	ElectrolytesIBA 04/2022 - 12/2016
3	Hematoxylin (Haematoxylon)IBA 12/2021 - 04/2012
3	Eosine Yellowish-(YS) (Eosin)IBA 12/2021 - 04/2012
3	cobaltous chloride (cobalt(II)chloride)IBA 01/2021 - 12/2016
3	Drinking WaterIBA 01/2021 - 01/2018
3	Monoclonal AntibodiesIBA 01/2020 - 09/2008
3	ChemokinesIBA 01/2020 - 07/2010
3	Metalloproteases (Metalloproteinases)IBA 01/2020 - 02/2014
3	MicroRNAs (MicroRNA)IBA 07/2019 - 02/2012
3	Biological ProductsIBA 02/2018 - 04/2013
3	LigandsIBA 01/2018 - 10/2009
3	Phenobarbital (Luminal)FDA Link 01/2017 - 09/2008
3	Matrix Metalloproteinase 9 (Gelatinase B)IBA 01/2017 - 12/2015
3	AntibodiesIBA 08/2015 - 08/2007
3	ErbB Receptors (EGF Receptor)IBA 06/2010 - 09/2008
2	RNA (Ribonucleic Acid)IBA 01/2021 - 01/2015
2	AcidsIBA 10/2020 - 01/2017
2	HMGB1 Protein (HMG1)IBA 10/2019 - 01/2017
2	Oxygen (Dioxygen)IBA 11/2018 - 06/2018
2	Interleukin-6 (Interleukin 6)IBA 06/2018 - 04/2012
2	Tissue Inhibitor of Metalloproteinase-1IBA 02/2018 - 11/2016
2	salicylhydroxamic acid (SHAM)IBA 01/2018 - 01/2017
2	Antimicrobial PeptidesIBA 01/2018 - 11/2009
2	OsteoprotegerinIBA 01/2018 - 01/2017
2	BilirubinIBA 12/2017 - 01/2016
2	SodiumIBA 01/2017 - 11/2016
2	etrolizumabIBA 02/2016 - 07/2014
2	heparanaseIBA 01/2016 - 12/2015
2	Nitric Oxide Synthase (NO Synthase)IBA 01/2016 - 04/2013
2	Syndecan-1 (Syndecan 1)IBA 12/2015 - 01/2014
2	cadherin 5IBA 03/2015 - 02/2015
2	Cadherins (E-Cadherin)IBA 03/2015 - 04/2011
2	ThrombospondinsIBA 02/2014 - 05/2013
2	Interleukin-8 (Interleukin 8)IBA 04/2011 - 07/2010
2	Cetuximab (Erbitux)FDA Link 10/2009 - 09/2008
1	C-Reactive ProteinIBA 04/2022
1	Janus Kinase InhibitorsIBA 01/2022
1	Proprotein Convertases (Pro-Opiomelanocortin Converting Enzyme)IBA 01/2022
1	FurinIBA 01/2022
1	tofacitinibIBA 01/2022
1	Oncostatin MIBA 10/2021
1	Mitochondrial DNA (mtDNA)IBA 10/2021
1	Dextran SulfateIBA 01/2021

Therapy/Procedure

22	Therapeutics 01/2022 - 04/2005
5	Restorative Proctocolectomy 06/2022 - 01/2008
4	Neoadjuvant Therapy 12/2021 - 09/2012
4	Transplantation 01/2021 - 11/2012
3	Colectomy 02/2010 - 09/2003
2	Esophagectomy 12/2021 - 12/2014
2	Vagus Nerve Stimulation 01/2021 - 01/2018